Units: 2Compares and contrasts cell-based and cell-free approaches to making and engineering commodity small molecules and genetically encoded biopolymers using naturally existing or biologically inspired enzymes. Both templated and non-templated synthetic systems will be explored. Includes biofuels production, drug discovery, protein engineering, and structural biophysics. Prerequisite(s):CHEM 401 and either CHEM 341 or CHEM 351.